Publication Type: | Journal Article |
Year of Publication: | 1973 |
Authors: | Ritchie, AE, Deshmukh, DR, Larsen, CT, Pomeroy, BS |
Journal: | Avian Diseases |
Volume: | 17 |
Issue: | 3 |
Date Published: | 1973 |
ISBN Number: | 00052086 |
Keywords: | Electron, Meleagris, Meleagris gallopavo, Phasianidae |
Abstract: | Particles morphologically similar to coronaviruses were found in bluecomb-infected turkey ceca, the bursa of Fabricius, and embryo intestines, but not in the same tissues of uninfected controls. The particles had diameters ranging from ca. 50 to >150 nm and bore variable numbers of pear- or club-shaped projections. None had a morphologically distinct organized internal component. The concentration of corona-virus-like particles (CVLP) was highest in embryo intestine and lowest in poult ceca and paralleled infectivity. The CVLP reacted specifically with antibodies in hyperimmune anti-bluecomb turkey serum but not with components of normal turkey serum or antibodies against 4 different coronaviruses. These CVLP appear to be characteristically associated with bluecomb disease and probably represent the infectious agent. Small oblate ellipsoidal particles, 20 × 45 nm, consisting of 2 curved portions fused at their ends were also uniquely associated with bluecomb infection and may represent viral precursors. |
URL: | http://www.jstor.org/stable/1589153 |
Short Title: | Avian Diseases |
Taxonomic name: